How You Know if You Have a Blood Clot in Your Leg

DVT (Claret Clot in the Leg, Deep Vein Thrombosis) Definition and Facts

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Illustration of a blood clot forming in a blood vessel.

Blood clots oft require medical treatment.

  • The definition of deep venous thrombosis (DVT) is a condition in which a blood clot is embedded in one of the major deep veins of the lower legs, thighs, pelvis, or arm. A jell blocks blood circulation through these veins, which carry blood from the lower body back to the heart. The blockage can cause astute pain, swelling, or warmth in the affected leg.
  • Claret clots in the veins tin cause inflammation (irritation) called thrombophlebitis.
  • Severe complications of deep vein thrombosis occur when a clot breaks loose (or embolizes) and travels through the bloodstream, causing blockage of blood vessels (pulmonary arteries) in the lung. Called pulmonary embolism (PE), this tin lead to severe difficulty in breathing and even death, depending on the degree of blockage.
  • The U.S. Centers for Disease Control and Prevention (CDC) estimates every bit many as 900,000 people could exist affected by DVT/PE each year in the United states, and 60,000 to 100,000 Americans die of DVT/PE (also chosen venous thromboembolism).
  • Symptoms and signs of DVT occur in the leg with the blood clot, and include:
    • Swelling
    • Pain
    • Redness
    • Warmth to the impact
    • Worsening leg hurting when bending the foot
    • Leg cramps (peculiarly at night and/or in the calf)
    • Discoloration of peel
  • Causes of deep vein thrombosis include damage to the inside of a blood vessel due to trauma or other conditions, changes in normal blood menstruum, or a rare land in which the blood is more likely than usual to clot (hypercoagulability).
  • Risk factors for DVT/PE include:
    • Prolonged sitting or immobility
    • Recent surgery
    • Contempo trauma to the lower body
    • Obesity
    • Centre attack or eye failure
    • Pregnancy or recent childbirth
    • High altitudes
    • Estrogen therapy or birth control pills
    • Cancer
    • Rare genetic weather that affect blood clotting factors
    • Sure middle or respiratory conditions
    • Advanced age
    • Medical conditions that bear upon the veins
  • Doctors diagnose the condition using imaging tests such as Doppler ultrasound, venography, impedance plethysmography, and CT scan.
  • Treatment of DVT in the leg is individualized for each patient. Usually, anticoagulation or blood-thinning medication is prescribed to prevent further clot formation and to minimize the risk that function of the blood clot will suspension off and travel to the lung and cause pulmonary embolism. New guidelines for diverse treatments were made past the ACCP (American Higher of Physicians) in 2016.
  • In rare cases, large deep venous thrombosis of the leg is treated with surgery in patients who cannot have blood thinners.
  • Prevention and prophylaxis of DVT involves managing risk factors.
    • Lose weight if overweight or obese
    • Avoid periods of prolonged immobility.
    • Keep the legs elevated while sitting down or in bed.
    • Avert high-dose estrogen pills.
    • Later surgery, go out of bed several times a day during the recovery period, use compression devices on the legs or elastic compression socks/stockings.
    • Take heparin or warfarin (Coumadin, Jantoven) if prescribed to prevent clot formation.

What Are the Alert Signs and Symptoms of a DVT?

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DVT (Blood Clot in the Leg)

Symptoms of DVT (claret clot in the leg) include swelling, pain, redness, warmth to the touch, leg cramps, or blue/whitish discoloration of the peel.

Signs and symptoms of a blood clot in the leg or deep vein thrombosis occur in the affected leg when a clot obstructs claret menses and causes inflammation. Signs and symptoms of DVT may include:

  1. Swelling
  2. Gradual onset of pain
  3. Redness
  4. Warmth to the touch
  5. Worsening leg pain when bending the foot
  6. Leg cramps, peculiarly at nighttime, and often starting in the calf
  7. Bluish or whitish discoloration of skin

Some people with deep vein thrombosis do not experience any symptoms.

What Causes DVTs?

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Causes of DVT

The three factors that may lead to blood clots are damage to the inside of a blood vessel, blockage of blood flow, and hypercoagulability (rare state).

Iii factors may pb to the formation of a clot inside a blood vessel:

  1. Impairment to the within of a claret vessel due to trauma or other conditions
  2. Changes in normal claret menstruation, including unusual turbulence, or partial or complete blockage of blood flow
  3. Hypercoagulability, a rare state in which the claret is more than likely than usual to clot

Any event or condition that can lead to blood vessel damage, hypercoagulability, or modify in blood menstruum can potentially cause deep vein thrombosis. The more common risk factors are:

  • Prolonged sitting, such equally during a long plane flight or car ride
  • Prolonged bed balance or immobility, such as after injury or during illness (for instance stroke)
  • Contempo surgery, particularly orthopedic (especially hip, leg, or , knee such as knee joint or hip replacement), gynecologic, heart, or abdominal surgery
  • Contempo trauma to the lower body, such as fractures of the bones of the hip, thigh, or lower leg
  • Obesity
  • Heart set on or middle failure
  • Pregnancy or recent childbirth
  • Existence at very high distance, greater than 14,000 anxiety
  • Use of estrogen therapy or nascency control pills
  • Cancer
  • Rare inherited genetic conditions that lead to changes in certain blood clotting factors
  • Sure center or respiratory conditions
  • Advanced historic period
  • Medical conditions that affect the veins such equally vasculitis (inflammation of the vein walls), varicose veins
  • Superficial venous thrombosis (SVT) occurs when a claret clot forms in a superficial vein nearly the surface of the torso. While non the aforementioned as DVT (which occurs in deep veins) it can be a gamble factor for DVT/PE
  • Disseminated intravascular coagulation (DIC), a medical condition in which blood clotting occurs inappropriately, ordinarily is caused by overwhelming infection or organ failure

If an individual has one deep vein thrombosis, they are 33% more probable to develop a 2nd deep vein thrombosis inside 10 years.

SLIDESHOW

Spider & Varicose Veins: Causes, Earlier and Afterward Treatment Images See Slideshow

When Is a DVT a Medical Emergency?

Telephone call the doctor immediately if a blood clot is suspected.

  • Although a deep vein thrombosis may resolve on its own, the life-threatening consequences of a clot reaching the lung, called pulmonary embolism, are severe enough to warrant seeking medical attention immediately.
  • The doctor may tell the patient to get immediately to a hospital emergency department.

If a person has leg pain or swelling with whatever risk factors, go to a hospital emergency section immediately.

Call 9-ane-one if yous or someone you know with a current deep vein thrombosis, previous deep vein thrombosis, or other DVT/PE risk factor begins having breast pain, shortness of breath, difficulty breathing, fainting, or any other concerning symptom.

Which Types of Doctors Treat DVTs?

The initial diagnosis of DVT is normally made past the general practitioner, internist, family practitioner, or an emergency medicine specialist.

Depending on the severity of the DVT/PE, or the demand for intervascular or surgical intervention, one may be referred to a vascular surgeon or an interventional radiologist. Other specialists involved in the intendance may involve a pulmonologist (a physician who specializes in the lungs), or a hematologist (specialist in blood disorders).

What Tests Diagnose DVTs?

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Upon hearing the patient'southward symptoms, the dr. may suspect the patient has a deep vein thrombosis, specially if any risk factors are present.

No accurate claret examination is available to diagnose deep vein thrombosis. A diversity of imaging tests are used to confirm the diagnosis.

  • Doppler ultrasound: Using high-frequency sound waves, this arrangement can visualize the large, proximal veins and detect a jell if one is present. Painless and without complications, this is the most commonly used method to diagnose deep vein thrombosis. Even so, sometimes the test tin can miss a jell, especially in the smaller veins.
  • Venography: A liquid dye is injected into the veins for imaging studies. It highlights blockage of claret period by a clot. This is the near accurate test, just also the most uncomfortable and invasive. It is rarely done today considering of the availability of improved ultrasound engineering science.
  • Impedance plethysmography: Electrodes are used to measure volume changes within veins. Considering this test does non notice clots better than ultrasound and is harder to perform, information technology is rarely used.
  • CT scan: This is a blazon of 10-ray that gives a very detailed look at the leg veins in cross section and can detect clots. It is rarely used for this purpose as it is more difficult to interpret and is fourth dimension consuming. The CT browse is more than useful for identification of blood clots in the lung.

What Is the Treatment for DVTs?

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The treatment of blood clots depends upon their location in the torso. Near normally, anticoagulation or blood-thinning medication is prescribed to forbid farther clot formation and to minimize the take chances that part of the blood jell will break off and travel to the lung and cause pulmonary embolism, or pulmonary embolism. Treatment of deep venous thrombosis in the leg is often individualized for each patient depending upon the clinical situation and other medical conditions that may exist present. The post-obit is how various drugs and therapies accept been used. New guidelines have been written in 2016 to help optimize treatments in patients with or without cancer, lower extremity DVT and pulmonary embolism, and for other private patient circumstances.

Treatment of deep venous thrombosis in the leg is often individualized for each patient depending upon the clinical situation and other medical atmospheric condition that may be present.

Anticoagulation is usual the treatment of option and is a two stage process. Low molecular weight heparin (enoxaparin [Lovenox], dalteparin [Fragmin]) injections are started to begin immediate blood thinning. At the same time, warfarin (Coumadin, Jantoven) is prescribed (an oral anticoagulation medication that takes a few days to become effective and adequately anticoagulate the blood). Blood tests (prothrombin time or international normalized ratio [INR]) are used to measure out the effectiveness of the warfarin therapy. When the INR reaches the appropriate level, the heparin injections are discontinued.

Rivaroxaban (Xarelto) is a medication called a selective Factor Xa inhibitor that is an oral tablet indicated for the treatment of DVT. Information technology may be used as a handling and a preventative prophylaxis for blood clots instead of warfarin.

Apixaban (Eliquis) and dabigatran (Pradaxa) also are drugs used to preclude blood clots and care for astute DVT.

If possible, the treatment of uncomplicated deep venous thrombosis in an individual is accomplished equally an outpatient. Didactics is provided to the patient and family to teach them how to administrate the injection, and the patient is instructed to render to their family unit doctor or the hospital for appropriate monitoring (blood tests). Some patients will need to be admitted to the hospital if they have meaning underlying medical illnesses, are meaning, or are unable to administer the heparin injections.

The duration of anticoagulation therapy depends upon the circumstances that led to the evolution of the blood jell. If in that location were temporary risk factors, for instance a long trip or recent immobility because of injury or affliction, treatment may terminal 3 to 6 months. Still, if the cause is unknown or if there is the risk for recurrent clot germination, medication may exist required for more than 12 months.

Not all DVTs require anticoagulation. Because modest clots located in veins below the knee accept a low adventure of embolizing to the lung, information technology can be possible to observe the patient without giving medications. Using serial ultrasound tests of the veins, the clot can exist monitored to run into whether it is extending and growing or whether it is stable and needs no further handling.

Blood clots located in the femoral vein near the groin that extend into the iliac vein in the abdomen may require more ambitious treatment with thrombolytic (thrombo=clot + lysis=breakup) therapy. Clot-busting drugs (alteplase [Activase], streptokinase [Streptase]) may be injected directly into the clot itself. This usually requires a specialist (a vascular surgeon or an interventional radiologist) who can apply fluoroscopy or existent time X-rays to position a catheter or tube into the afflicted vein where the clot resides and drip the medication in over a period of time to dissolve the clot and prevent it from traveling to the lung.

Similar situations can exist in the arm. DVTs higher up the elbow are usually treated with claret-thinner medications as described above, while clots in the subclavian vein, located just beneath the collarbone, may exist considered for thrombolytic therapy.

Because of underlying medical weather, some people may not be able to take anticoagulation medications and may require an alternative treatment instead of medication. Those who have gastrointestinal bleeding (haemorrhage from the stomach or bowel), intracranial haemorrhage (bleeding within the brain or surrounding tissues), or who accept had contempo major trauma potentially could bleed to death if anticoagulation medications are prescribed. The alternative for leg DVT treatment in these situations may be an inferior vena cava filter. The vena cava is the large vein that collects blood from the lower body simply before it enters the center. A filter can be placed into the vena cava to trap any clots that might pause off and preclude them from traveling to the center and then to the lungs.

Compression stockings or socks are useful in preventing a complication of a leg blood clot called mail-thrombotic syndrome or postphlebitis syndrome, in which the affected leg swells and becomes chronically painful. These stockings may be purchased over-the-counter or can exist custom fitted. It is recommended they be worn for at least a yr later on the diagnosis of deep venous thrombosis.

What Medications Treat DVTs?

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Warfarin (Coumadin) is an oral medication taken to thin or anticoagulate the blood. Information technology may have a few days for its activity to take effect. The dose needs to be individualized for each person, and claret clotting must exist monitored routinely since changes in nutrition, activity, and the administration of other medications may bear on the levels of warfarin. Blood tests (usually international normalized ratio [INR]) are done routinely to monitor the claret-thinning furnishings and assist the wellness care professional select the advisable warfarin dose. Ideally, the INR should exist kept in a range between 2.0 and three.0. Blood tests are done weekly until the INR stabilizes so are done every 2 weeks to every month.

Enoxaparin (Lovenox) is a low molecular weight heparin injected below the skin to sparse the blood. The dose is usually 1 milligram per kilogram of weight injected twice daily or ane.5 milligrams per kilogram injected once daily. Enoxaparin ordinarily is considered a temporary medication to exist used to thin the claret while warfarin begins to take effect; notwithstanding, it may be used over the long term in some patients with cancer. Fondaparinux (Arixtra) is another injectable chemically related to low molecular weight heparin, used for DVT prevention and treatment.

If a woman develops a DVT/PE while meaning it is commonly treated with heparin only, because warfarin is unsafe to administrate during pregnancy.

Rivaroxaban (Xarelto) is a newer medication, which belongs to the selective Factor Xa inhibitor class of drugs, is an oral tablet for the treatment of DVT. Information technology may exist used as a handling and a preventive therapy for blood clots.

Apixaban (Eliquis), dabigatran (Pradaxa), and Edoxaban (Savaysa, Lixiana) are too used to prevent claret clots and care for acute DVT.

When Is Surgery Necessary for a DVT?

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Surgery is a rare selection in treating large deep venous thrombosis of the leg in patients who cannot take blood thinners or who take developed recurrent blood clots while on anticoagulant medications. The surgery is unremarkably accompanied by placing an IVC (inferior vena cava) filter to prevent future clots from embolizing to the lung.

Phlegmasia cerulea dolens describes a situation in which a blood clot forms in the iliac vein of the pelvis and the femoral vein of the leg, obstructing nigh all blood return and compromising blood supply to the leg. In this case surgery may be considered to remove the jell, just the patient volition as well crave anticoagulant medications.

QUESTION

Deep vein thrombosis (DVT) occurs in the _______________. See Reply

Practise I Demand to Follow-upwardly with My Medico Later on DVT Treatment?

A person who has had a deep vein thrombosis may be asked to return for follow-upwards. Doppler ultrasounds or other imaging studies may be performed if the leg swelling persists or if the symptoms recur. During anticoagulant treatment, it is often advised to take the following measures:

  • Take the prescribed corporeality of medication equally directed by a physician. Do not miss or add doses.
  • Follow the doc'southward instructions closely well-nigh when to get lab tests for blood coagulation.
  • Inquire the physician before starting or stopping any medication or supplement, including over-the-counter (OTC) medications. Many medicines and supplements increase or otherwise interfere with the effect of anticoagulants.
  • Ask what foods should be avoided, considering some foods may modify the effectiveness of blood-thinning drugs.
  • Wearing a MedicAlert bracelet with information well-nigh whatever anticoagulants one is taking is advised.
  • People on anticoagulant therapy should inform any other medical professionals including dentists or podiatrists before undergoing any procedure.

What Is the Risk of Having Another DVT?

Nigh DVTs resolve on their own. If a pulmonary embolism (PE) occurs, the prognosis tin be more astringent.

  • About 25% of people who have a PE volition die all of a sudden, and that volition exist the merely symptom.
  • About 23% of people with PE will dice within 3 months of diagnosis, just over 30% will die after 6 months, and there is a 37% bloodshed (death) rate at 1 year after being diagnosed.

If an individual has had one deep vein thrombosis, they are more likely than the boilerplate person to take another deep vein thrombosis.

  • The CDC estimates 33% of people with DVT/PE volition accept a recurrence within 10 years.
  • Recurrence of DVT is more common in patients with risk factors such as cancer or inherited blood-clotting issues. Recurrence is less mutual in patients who have brusk-term risk factors, such as surgery or temporary inactivity.
  • Closely follow the prevention instructions from the physician.
  • Anticoagulant therapy lowers the death rate from pulmonary embolism significantly.

How Can a DVT Exist Prevented?

The cardinal to prevention of DVT is to reverse any risk factors, for example:

  • Lose weight if overweight or obese.
  • Avoid periods of prolonged immobility. Become upwards and move around every 15 to 30 minutes during long airplane flights. Practise simple stretching exercises while seated. Make frequent stops and get out of the car when driving long distances.
  • Keep the legs elevated while sitting downwardly or in bed.
  • Avoid high-dose estrogen pills, unless they are deemed necessary by the doctor.

In the example of recent surgery, preventive treatment may be prescribed to avert germination of a clot.

  • The patient may be instructed to exit of bed several times a twenty-four hour period during the recovery period.
  • Sequential compression devices (SCDs) may be placed on the legs. Their squeezing action has been shown to reduce the probability of clot formation. The patient may besides be given elastic compression socks or stockings to habiliment.
  • Low-molecular-weight heparin or low-dose warfarin may exist prescribed to foreclose clot formation.

DVT picture

What Are the Symptoms and Signs of a Pulmonary Embolism (Blood Jell in the Lung)?

Warning signs and symptoms of a blood clot in the lung or pulmonary embolism include:

  1. A very sharp stabbing pain in the chest
  2. Shortness of breath.
  3. Cough.
  4. Sweating.
  5. Passing out.

A blood clot in the lung is a medical emergency and needs to exist treated right away.

Reviewed on 6/4/2020

References

LiP, GYH Md. Arroyo to the diagnosis and therapy of lower extremity deep vein thrombosis. UpToDate. Updated: Sep 29, 2019.
<https://www.uptodate.com/contents/arroyo-to-the-diagnosis-and-therapy-of-lower-extremity-deep-vein-thrombosis>

Centers for Disease Control and Prevention. Venous Thromboembolism. (Blood Clots).

FDA Prescribing Information. SAVAYSA™ (edoxaban).
<http://www.accessdata.fda.gov/drugsatfda_docs/characterization/2015/206316lbl.pdf>

FDA Prescribing Information. ARIXTRA® (fondaparinux sodium) infection.
<http://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021345s010lbl.pdf>

Dentali, F., et al. "Pulmonary embolism severity index accurately predicts long-term bloodshed rate in patients hospitalized for acute pulmonary embolism."

Journal of Thrombosis and Haemostasis

. xi.12 (2013): 2103-2120.

Litzendorf, M. E. and B Satiani. "Superficial venous thrombosis: illness progression and evolving treatment approaches." Vascular Health and Hazard Management. vii (2011): 569-575.

Lucena, J., et al. "Pulmonary embolism and sudden-unexpected death: prospective written report on 2477 forensic autopsies performed at the Institute of Legal Medicine in Seville." Journal of Forensic and Legal Medicine. sixteen.iv (2009): 196-201.

MedlinePlus. Deep Vein Thrombosis. Thompson, B.T., Physician. "Overview of acute pulmonary embolism in adults." Updated: Aug 08, 2016.
<http://www.uptodate.com/contents/overview-of-acute-pulmonary-embolism-in-adults>

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